Related Experiment Video
Updated: Aug 14, 2026

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae
Published on: May 10, 2014
Cystic fibrosis: can epithelial function be restored?
1Royal Free & University College Medical School, Rowland Hill Street, London, NW3 2PF, UK. s.trapp@rfc.ucl.ac.uk
Abstract:
The treatment of cystic fibrosis (CF) is still very much concerned with alleviating its symptoms. However, despite the considerable increase in the knowledge of the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, no magic bullet for the treatment of CF is in sight. This review focuses on what is known about the ion transport defect and which pharmacological and molecular approaches have the greatest potential to provide a cure in the future.

