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Updated: Jul 18, 2026
06:55
Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
Mortality in Barrett's oesophagus: results from a population based study
L A Anderson1, L J Murray, S J Murphy
1Northern Ireland Cancer Registry, Department of Epidemiology and Public Health, The Queen's University Belfast, UK. l.anderson@qub.ac.uk
Gut
|July 17, 2003
Summary
Barrett's oesophagus patients have similar overall mortality to the general population. While oesophageal cancer risk is elevated, it's an uncommon cause of death, with reduced stroke mortality observed.
Area of Science:
- Gastroenterology
- Oncology
- Epidemiology
Background:
- Barrett's oesophagus increases oesophageal adenocarcinoma risk, but cancer is a minor cause of death.
- Other causes of mortality may be elevated in Barrett's patients.
Purpose of the Study:
- To examine cause-specific mortality in individuals within a population-based Barrett's oesophagus registry.
Main Methods:
- A registry of oesophageal columnar mucosa diagnoses (1993-1999) in Northern Ireland was created.
- Deaths in the cohort until December 2000 were identified and compared to general population mortality rates.
Main Results:
- Overall mortality was not elevated in Barrett's patients (SMR 96).
- Oesophageal cancer mortality was significantly raised (SMR 774) but accounted for only 4.7% of deaths.
- Stroke mortality was lower (SMR 65), and non-cancerous digestive disease mortality was higher (SMR 211).
Conclusions:
- Overall mortality in Barrett's oesophagus patients mirrors the general population.
- Oesophageal cancer is an infrequent cause of death despite increased risk.
- Barrett's patients may have a reduced risk of death from stroke.
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