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[Possibilities of spontaneous regression in active phase of ROP]
1Centrum Okulistyki Dzieciecej w Warszawie.
Insights
Spontaneous regression of retinopathy of prematurity (ROP) varies by stage and retinal zone. Laser therapy is recommended for specific ROP stages and zones to prevent vision loss.
Area of Science:
- Ophthalmology
- Neonatal care
- Retinal diseases
Context:
- Retinopathy of prematurity (ROP) affects premature infants.
- Active ROP presents in stages 1-5.
- Early detection and intervention are crucial for visual outcomes.
Purpose:
- To assess spontaneous regression rates in active retinopathy of prematurity (ROP) stages 1-5.
- To correlate regression with ROP stage and retinal zone involvement.
- To inform treatment decisions for ROP.
Summary:
- Spontaneous regression of ROP was observed in 85% (stage 1), 56% (stage 2), and 25% (stage 3).
- Regression rates decreased with ROP progression and involvement of peripheral retinal zones (Zone I: 6%, Zone II: 45%, Zone III: 95%).
- Spontaneous retinal reattachment occurred in 27% (stage 4A), 15% (stage 4B), and 6% (stage 5).
Impact:
- Findings guide the judicious application of laser therapy in ROP.
- Early intervention is emphasized for ROP in Zone I and advanced stages (3B, 3C).
- Optimizing ROP treatment can improve long-term visual prognosis in premature infants.
Purpose:
To evaluate the possibilities of spontaneous regression of changes in the retina and vitreous in active stage 1-5 retinopathy in prematurity.
Material And Methods:
168 premature infants with active stages 1-3 and 91 with stages 4-5 ROP, was observed by the author in years 1995-2002.
Results:
Spontaneous regression of changes in the retina and vitreous was observed in 85% of children with stage 1, in 56% in stage 2 and in 25% in stage 3. In stage 3 regression occurred in 35% in stage 3 A, in 18% in 3 B and in 12% in stage 3 C. With changes in zone III regression can be expected in 95%, in zone II in 45% and in zone I in 6%. Spontaneous reattachment of the retina was observed in 27% of children with stage 4A, in 15% with stage 4B and only in 6% in stage 5.
Conclusions:
Considering the occurrence of spontaneous regression, laser therapy should be performed in every stage, if changes are observed in zone I and in every case of stage 3 B and 3 C.