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Related Experiment Videos

Eosinophilic Meningitis.

Trevor Slom1, Stuart Johnson

  • 1Hines VA Hospital/151, Fifth Avenue & Roosevelt Road, Hines, IL 60141, USA. sjohnson@lumc.edu

Current Infectious Disease Reports
|July 18, 2003
PubMed
Summary
This summary is machine-generated.

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Angiostrongylus cantonensis (Angiostrongylus cantonensis) infection causes eosinophilic meningitis (EM). This study highlights the Caribbean as an emerging endemic region, with steroid therapy proving effective for headache management.

Area of Science:

  • Medical Parasitology
  • Infectious Diseases
  • Neurology

Background:

  • Eosinophilic meningitis (EM) presents with diverse etiologies, both infectious and noninfectious.
  • Angiostrongylus cantonensis (Angiostrongylus cantonensis) is the predominant infectious cause of EM globally.
  • Traditional endemic regions include Southeast Asia and the Pacific Islands.

Purpose of the Study:

  • To investigate the emergence of Angiostrongylus cantonensis-associated EM in the Caribbean.
  • To assess the clinical presentation and management strategies for this parasitic meningitis.

Main Methods:

  • Review of clinical cases and outbreak investigations.
  • Parasitologic surveys of intermediate and paratenic hosts (snails and rats).

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Main Results:

  • Confirmed Angiostrongylus cantonensis as a cause of EM in travelers returning from Jamaica.
  • Identified the Caribbean as a newly recognized endemic region for Angiostrongylus cantonensis.
  • Observed that eosinophilia is not consistently present in early stages of infection.
  • Demonstrated the safety and efficacy of steroid therapy for headache relief in adult patients.

Conclusions:

  • Angiostrongylus cantonensis poses an increasing risk in the Caribbean.
  • Early diagnosis and management, including intracranial pressure control, are crucial.
  • Steroid therapy offers a safe and effective approach for symptomatic relief of headache.