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Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to
John L Sorensen1, John C Vederas
1Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
Chemical Communications (Cambridge, England)
|July 19, 2003
Abstract:
A novel compound, monacolin N, has been isolated from fermentation cultures of Aspergillus nidulans in which the lovastatin polyketide synthase genes lovB and lovC are heterologously expressed.