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Updated: Aug 10, 2026

Orthotopic Liver Transplantation in Rats
Published on: July 1, 2012
Successful twin pregnancy after orthotopic liver transplantation
Júlio Cezar Uili Coelho1, Mônica Beatriz Parolin, Jorge E Fouto Matias
1Department of Surgery and Gynecology and Obstetrics, Federal University of Parana, Curitiba, PR, Brazil.
Aim:
Report of a case of successful twin pregnancy following liver transplantation.
Patient And Method:
A 42-year-old nulliparous-woman was subjected to an orthotopic liver transplantation due to Budd-Chiari syndrome. Sixteen months after the transplantation, an ultrasonography revealed twin pregnancy. Her prenatal course was uneventful, except for mild arterial hypertension. The immunosuppressive agents used during pregnancy were cyclosporine and prednisone.
Result:
The patient gave birth to two healthy girls at 37 weeks of gestation. The patient's postpartum course was uneventful with normal liver and renal function tests.
Conclusion:
Following successful pregnancy, women may become pregnant and give birth to normal children, including twins
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