[Juvenile papillomatosis of the breast]
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Updated: Sep 23, 2026
![Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60445.jpg&w=3840&q=50)
Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)
Published on: December 19, 2019
P Noccioli1, S Grossi, A D'Aulerio
1U.O. di Senologia Chirurgica, Dipartimento di Scienze Chirurgiche Sperimentali, Cliniche dell'Università G. d'Annunzio di Chieti P.O. G. Bernabeo di Ortona.
Abstract:
The PJ, introduced by Rosen in the 1980, is a benign and localized mammary lesion in female under 30 years old. The most important clinical and histological features are: Diagnosis in juvenile age. A mass clinically localized. A nodule with histologic features of cyst, benign hyperplasia of ductal epithelium and galactophorus ducts dilatation (Swiss cheese disease). There is a correlation between patients with PJ and breast cancer there is an increment of breast cancer in familirs of patients with PJ. There is an increment of the risk to develop a K in situ in patients with PJ and apocrine metaplasia and/or adenomatosis and/or atypical mastoplasia. We describe the diffuse PJ in a girl of 23 years old from the 1996 to 2002.
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