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Related Experiment Videos

Is pain fatiguing? A structured evidence-based review.

David A Fishbain1, Brandley Cole, R B Cutler

  • 1University of Miami, School of Medicine, Miami Beach, Florida, USA. d.fishbain@miami.edu

Pain Medicine (Malden, Mass.)
|July 23, 2003
PubMed
Summary

This review found a strong association between fatigue and pain, suggesting a potential cause-and-effect relationship. Healthcare professionals should recognize fatigue

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Area of Science:

  • Medical Research
  • Pain Management
  • Clinical Psychology

Background:

  • Fatigue is a common complaint among chronic pain patients.
  • Previous studies suggest an association between fatigue and pain.

Purpose of the Study:

  • To investigate the evidence for an association between fatigue and pain.
  • To explore a potential etiological relationship between pain and fatigue.

Main Methods:

  • A structured, evidence-based review of 23 studies on fatigue and pain.
  • Studies were assessed for quality using 15 criteria (AHCPR guidelines).
  • Only studies with quality scores of 75% or greater were included.

Main Results:

  • 94.1% of high-quality studies (17 reports) indicated an association between fatigue and pain.

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  • 100% of a subgroup of 13 high-quality reports suggested a potential etiological link.
  • Evidence strength and consistency were categorized as 'A' (highly consistent).

    • Conclusions:

    • A significant association exists between fatigue and pain.
    • A potential etiological relationship between pain and fatigue is supported by evidence.
    • Clinicians should be aware of fatigue's prevalence in pain patients.