Related Experiment Video
Updated: Aug 12, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
Published on: May 7, 2010
Long-range doublet correlations in DNA and the coding regions
1Department of Theoretical Physics, Schuster Laboratory, University of Manchester, U.K.
Abstract:
Long-range two-body correlations in a DNA sequence should in theory approach a constant value very rapidly with increasing value of the correlation length. It is shown that for most DNA sequences, the long-range correlations exhibit oscillations superimposed on the constant background. These oscillations persist for very large correlation lengths. The oscillations are shown to be three-point cycles and are related to the coding regions in the DNA. A method for discovering the coding regions in DNA sequences is presented. The limitations of the method are discussed.
Related Concept Videos
The DNA Helix
DNA Base Pairing
DNA as a Genetic Template
DNA Base Pairing
¹H NMR: Long-Range Coupling
In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene π orbitals.
DNA as a Genetic Template

