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Factors associated with poor outcome in children with acute otitis media
Hiroko Monobe1, Toshio Ishibashi, Yoshinori Fujishiro
1Department of Otolaryngology, University of Tokyo, Tokyo, Japan.
Insights
Young children under 2 years old and those with persistent middle ear fluid after treatment require close follow-up for acute otitis media (AOM) to prevent poor outcomes and recurrence.
Area of Science:
- Pediatrics
- Infectious Diseases
- Otolaryngology
Background:
- Acute otitis media (AOM) is a common childhood infection.
- Identifying factors for poor outcomes in AOM is crucial for effective management.
- Persistent middle ear effusion and recurrent AOM pose significant clinical challenges.
Purpose of the Study:
- To determine key factors associated with adverse outcomes in pediatric AOM.
- To investigate the influence of age, nursing, breastfeeding, and bacterial presence on AOM prognosis.
- To identify risk factors for persistent middle ear fluid, early recurrence, and recurrent AOM.
Main Methods:
- A cohort of 73 pediatric patients with AOM was studied.
- Factors analyzed included age, gender, group nursing, siblings, breastfeeding duration, and bacterial isolates.
- Statistical analyses (univariate and multivariate) were employed to identify significant predictors.
Main Results:
- Children under 2 years old had a higher risk of recurrent AOM.
- Absence of group nursing was linked to early AOM recurrence.
- Persistent middle ear fluid correlated significantly with recurrent AOM.
- Bacterial species did not influence clinical outcomes.
Conclusions:
- Children younger than 2 years require vigilant, long-term monitoring for AOM.
- Persistent middle ear effusion necessitates close follow-up to manage potential recurrence.
- Early identification of at-risk children can guide targeted interventions for better AOM management.
Objective:
To identify factors determining poor outcome in children with acute otitis media (AOM).
Material And Methods:
We considered the following factors in children with AOM: age; gender; the presence of group nursing; the presence of siblings; the duration of breastfeeding; and the type of bacteria isolated from the middle ear fluid (MEF) or nasopharynx. The 73 pediatric patients studied included 61 examined in outpatient clinics and 12 seen at a children's home.
Results:
Of the 61 children examined in outpatient clinics, 32 (52%) had persistent MEF (fluid accumulation in the middle ear persisting for up to 1 month after treatment); 14 (23%) had early recurrence of AOM (within 1 month following an initial improvement); and 14 (23%) developed recurrent AOM (> 3 recurrences during 6 months of follow-up). Using univariate and multivariate analyses, age < 2 years was found to be significantly related to the development of recurrent AOM and an absence of group nursing was found to be significantly related to the development of early recurrence. Persistent MEF was significantly related to the development of recurrent AOM. There was no difference between bacterial species isolated from the MEF or nasopharynx in terms of clinical outcome.
Conclusions:
These findings indicate that particularly close long-term follow-up is necessary for children aged < 2 years and children with a middle ear effusion that persists for up to 1 month after treatment.
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