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Cortical resection for epilepsy in children with linear sebaceous nevus syndrome
Cormac O Maher1, Aaron A Cohen-Gadol, Corey Raffel
1Department of Neurosurgery, Mayo Clinic, Rochester, Minn., USA. maher.cormac@mayo.edu
Abstract:
Linear sebaceous nevus syndrome (LSNS) is a rare neurocutaneous syndrome that is associated with seizures and mental retardation. The cortical abnormalities that are associated with this syndrome include focal cortical dysplasia, partial hemimegalencephaly and holohemispheric hemimegalencephaly. Few reports have addressed the utility of cortical resections for epilepsy treatment in the setting of LSNS. We report 3 children with this syndrome who underwent extensive cortical resections and experienced significant improvement in seizure frequency. Our results support the utility of extensive cortical resections for children with this condition.