Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming

The Legionella pneumophila effector SidL is an adenylyltransferase that modifies the glycolytic intermediate 3-phosphoglycerate.

Molecular cell·2026

Raising Male Drones Affects Honey Bee (Apis mellifera) Foraging Behavior.

Integrative and comparative biology·2026

Differential Hydroxypyruvate Processing by E. coli and P. aeruginosa DXP Synthases Reveals Preferential Xylulose 5-Phosphate Formation by the P. aeruginosa Enzyme.

Biochemistry·2026

Growth hormone receptor antagonism improves tumoral chemo-immunotherapy response in a mouse model of lung cancer.

Translational oncology·2026

Lymphatic pumping technique in mice alters blood parameters and metastatic melanoma in an age-dependent manner.

Experimental biology and medicine (Maywood, N.J.)·2026

Aromatic Residues in Mobile Regions Distal to the Active Site Support the Closed Conformation of E. coli DXPS.

Biochemistry·2026

Neutral Backbone Modifications Enhance the Pharmacokinetics and Biodistribution of Antibody-Oligonucleotide Conjugates with High Drug-to-Antibody Ratios.

Journal of medicinal chemistry·2026

Discovery of TL10: A Soluble and Long-Acting MC4R Agonist with Tunable Lipidation for Sustained Pharmacological Activity.

Journal of medicinal chemistry·2026

Discovery, Synthesis, and Biological Evaluation of 1,3,4,5-Tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one Derivatives as Novel and Highly Selective PARP1 Inhibitors.

Journal of medicinal chemistry·2026

Discovery and Optimization of Novel Nonhydroxamate LpxC Inhibitors for the Treatment of Multidrug-Resistant Gram-Negative Infections.

Journal of medicinal chemistry·2026

Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8.

Journal of medicinal chemistry·2026

Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight.

Journal of medicinal chemistry·2026

Tuning Hopeite-Phase Dominant Phosphate Coating with Dy-Doped MoS2 for Improved Antibacterial Surface Protection.

ACS applied bio materials·2026

Engineering Multilayer Poly(ethylene glycol) Hydrogels via Off-Stoichiometry Thiol-Ene Chemistry.

ACS applied polymer materials·2026

Fate patterns originate through structural relations between cell and supracellular levels of organization.

bioRxiv : the preprint server for biology·2026

Translocon Remodeling Modulates Ribosomal Frameshifting and the Maturation of the Sindbis Virus Structural Polyprotein.

bioRxiv : the preprint server for biology·2026

Defect-engineered pollen-shaped WO3 with interfacial catalysis toward sensitive humidity-tolerant DMTS detection.

Analytical methods : advancing methods and applications·2026

Upcycling Fungal Mycelium Into Hard Carbon With Zn-Engineered Graphitic Nanodomains for Ultrafast Sodium Storage.

Small (Weinheim an der Bergstrasse, Germany)·2026

Related Experiment Videos

Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming

Related Concept Videos

The Legionella pneumophila effector SidL is an adenylyltransferase that modifies the glycolytic intermediate 3-phosphoglycerate.

Raising Male Drones Affects Honey Bee (Apis mellifera) Foraging Behavior.

Differential Hydroxypyruvate Processing by E. coli and P. aeruginosa DXP Synthases Reveals Preferential Xylulose 5-Phosphate Formation by the P. aeruginosa Enzyme.

Growth hormone receptor antagonism improves tumoral chemo-immunotherapy response in a mouse model of lung cancer.

Lymphatic pumping technique in mice alters blood parameters and metastatic melanoma in an age-dependent manner.

Aromatic Residues in Mobile Regions Distal to the Active Site Support the Closed Conformation of E. coli DXPS.

Neutral Backbone Modifications Enhance the Pharmacokinetics and Biodistribution of Antibody-Oligonucleotide Conjugates with High Drug-to-Antibody Ratios.

Discovery of TL10: A Soluble and Long-Acting MC4R Agonist with Tunable Lipidation for Sustained Pharmacological Activity.

Discovery, Synthesis, and Biological Evaluation of 1,3,4,5-Tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one Derivatives as Novel and Highly Selective PARP1 Inhibitors.

Discovery and Optimization of Novel Nonhydroxamate LpxC Inhibitors for the Treatment of Multidrug-Resistant Gram-Negative Infections.

Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8.

Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight.

Tuning Hopeite-Phase Dominant Phosphate Coating with Dy-Doped MoS2 for Improved Antibacterial Surface Protection.

Engineering Multilayer Poly(ethylene glycol) Hydrogels via Off-Stoichiometry Thiol-Ene Chemistry.

Fate patterns originate through structural relations between cell and supracellular levels of organization.

Translocon Remodeling Modulates Ribosomal Frameshifting and the Maturation of the Sindbis Virus Structural Polyprotein.

Defect-engineered pollen-shaped WO3 with interfacial catalysis toward sensitive humidity-tolerant DMTS detection.

Upcycling Fungal Mycelium Into Hard Carbon With Zn-Engineered Graphitic Nanodomains for Ultrafast Sodium Storage.

Related Experiment Videos

Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming

Related Concept Videos

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