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Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
Published on: October 12, 2012
Precision of INR measured with a patient operated whole blood coagulometer
Jørn Attermann1, Niels T Andersen, Helle Korsgaard
1Department of Biostatistics, University of Aarhus, Vennelyst Boulevard 6, DK-8000 Aarhus C, Denmark. jorn.attermann@bisam.dk
Introduction:
The objective of the present study was to evaluate the precision of a portable whole blood coagulometer (CoaguChek S) in the hands of self-managing patients on oral anticoagulant therapy (OAT).
Materials And Methods:
Fifteen patients on self-managed OAT performed measurements of INR by two types of portable whole blood coagulometers (CoaguChek and CoaguChek S) at home for 10 weeks.
Results:
The coefficient of variation (CV) of INRs determined at home by CoaguChek S by patients on self-managed OAT was 5.5% (95% confidence limits: 4.9%, 6.1%). The biological CV of INR within and between patients was 15.0% and 14.7%, respectively.
Conclusion:
The precision of CoaguChek S is satisfactory.
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