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Related Experiment Videos

Psoriatic nails: a prospective clinical study.

Joanna Salomon1, Jacek C Szepietowski, Alina Proniewicz

  • 1Department of Dermatology and Venereology, University of Medicine, Wrocław, Poland.

Journal of Cutaneous Medicine and Surgery
|July 25, 2003
PubMed
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Nail changes are common in psoriasis, particularly in arthropathic psoriasis patients. Subungual hyperkeratosis and pitting are typical, but fungal infections are difficult to confirm in psoriatic nails.

Area of Science:

  • Dermatology
  • Clinical Medicine
  • Mycology

Background:

  • Psoriasis frequently affects nails, often mimicking fungal infections (onychomycosis).
  • Nail changes are a common but often overlooked symptom in psoriasis patients.
  • Understanding nail involvement is crucial for comprehensive psoriasis management.

Purpose of the Study:

  • To determine the frequency and types of nail changes in psoriasis patients.
  • To explore correlations between nail involvement and clinical psoriasis parameters.
  • To assess the prevalence of fungal nail infections in this population.

Main Methods:

  • Dermatological examination of 106 hospitalized psoriasis patients.
  • Detailed assessment of nail abnormalities.

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  • Mycological investigations for suspected fungal infections.

    • Main Results:

    • Nail changes observed in 78.3% of patients.
    • Subungual hyperkeratosis, onychorrexis, and discoloration were common.
    • Psoriatic nail dystrophy was more frequent in older patients and those with arthropathic psoriasis.
    • Fungal cultures were positive in 18% of patients with nail changes, predominantly molds.

    Conclusions:

    • Psoriatic nail dystrophy is common, especially in arthropathic psoriasis.
    • Subungual hyperkeratosis and pitting are characteristic nail lesions.
    • The role of psoriasis as a predisposing factor for fungal nail infections requires further investigation.