[Morphology and morphogenetic mechanisms of brain lesions in acute generalized peritonitis]

Pronounced alterations of brain elements (vessels, neurocytes, glial cells, neural fibers and synaptic apparatus) are observed in acute generalized peritonitis. The following morphological forms of peritoneal encephalopathy were recognized: diffuse-focal lesions, incomplete partial necroses, inflammatory changes in the form of meningitis and encephalitis. The morphological changes were provoked by some factors resultant from developing endotoxicosis and homeostatic disorders. Structural disturbances may play a leading role in polyorganic insufficiency and under certain conditions may have an independent tanatogenetic significance.