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Carbaryl distribution in rabbit tissues and body fluids
J Malvisi1, A Zaghini, G L Stracciari
1Instituto di Farmacologia, Farmacocinetica e Tossicologia, Facolta di Medicina Veterinaria, Universita degli Studi di Bologna, Italy.
Veterinary and Human Toxicology
|December 1, 1992
Abstract:
After single po administration of 14C-naphthylcarbamate, liquid scintillation assays evaluated the distribution of carbaryl in rabbit serum, liver, kidneys, small and large intestine, spleen, heart, muscles of the thigh and lungs and its excretion in urine and feces at 2, 4, 6 and 8 h after dosing. At 2 and 8 h radioactivity was not observed in spleen, heart, muscle and lungs, while all other tissues had increased values up to 6 h. The main excretory pathway of carbaryl was the kidneys.