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Updated: Aug 19, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
[Chronic psychoemotional stress and its effect on population health]
Abstract:
Consideration is given to the quantitative characteristics of health effects of the chronic psychoemotional stress associated with the economic and social status of one's family, and profession. The study was performed with the use of a model of decline in the human body compensatory reserve on a background of single or combined stresses. On a population scale, this can be seen in a regular growth of the death coefficient in various age groups and an increase of the mean death coefficient in regional and whole country populations. Analyzed were the psychoemotional and health implications of the level of per capita income in a family with full employment of able to work members, unemployment, some natural disasters, and type of occupation. Ageing and death coefficient trends in several regions of the country were correlated on a basis of the analysis of single and combined chronic effects of radiation, chemical pollution, altered economic and social status, and type of occupation. The author speculates on changes in morbidity, total risk of death and possible reduction of the life expectancy caused by the multitude of the above-mentioned negative factors.
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