Multitasking with molecular dynamics Typhoon: quantifying nucleic acids and autoradiographs
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Updated: Sep 20, 2026
Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
Published on: March 1, 2022
Robert J Goodrich1, G Charles Ostermeier, Stephen A Krawetz
1Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI 48201, USA.
Abstract:
With increased sensitivity and specificity, fluorescent assays are rapidly becoming the method of choice for nucleic acid quantification. The utility of the Typhoon scanner has now been extended to accurately measure low levels of DNA and RNA (5 ng ml(-1)) with PicoGreen and RiboGreen dyes. In addition, with a few simple modifications, autoradiographic film images can be scanned and quantified with the Typhoon series of scanners.
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