Related Experiment Videos
[Transient dysfunction of the retinal ganglion cells after laser in situ keratomileusis]
Fan Wang1, Nobuyuki Shoji, Kimiya Shimizu
1Department of Ophthalmology, China-Japan Union Hospital, Ji Lin University, Japan.
Purpose:
To evaluate the influence of high intraocular pressure(IOP) on the retinal ganglion cell function induced by suction during laser in situ keratomileusis(LASIK) using Frequency Doubling Technology(FDT).
Methods:
Twenty-seven eyes of 15 patients were studied. Threshold values of 19 targeted areas, mean deviation(MD), and pattern standard deviation (PSD) were measured before LASIK, and 2 hours, 1 day, and 1 week after LASIK. These parameters obtained by N-30 program of FDT were compared between before and after LASIK.
Results:
Significant decrease of MD and threshold value in all areas was recognized at 2 hours, but MD and threshold value in 6 of the 19 areas showed significant increase at 24 hours. Significant increase of PSD value at 2 hours was recognized. After 7 days, there were no significant differences in any parameters between before and after LASIK.
Conclusion:
These results indicated that a transient dysfunction of the magnocellular pathway might be induced by high IOP during LASIK procedure.