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Lentiviral-mediated Knockdown During Ex Vivo Erythropoiesis of Human Hematopoietic Stem Cells
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Recombinant erythropoietin in clinical practice

T Ng1, G Marx, T Littlewood

  • 1Phase One Clinical Trials Unit Ltd, Plymouth, UK. tsfng@hotmail.com

Postgraduate Medical Journal
|August 5, 2003
PubMed

The introduction of recombinant human erythropoietin (RHuEPO) has revolutionised the treatment of patients with anaemia of chronic renal disease. Clinical studies have demonstrated that RHuEPO is also useful in various non-uraemic conditions including haematological and oncological disorders, prematurity, HIV infection, and perioperative therapies. Besides highlighting both the historical and functional aspects of RHuEPO, this review discusses the applications of RHuEPO in clinical practice and the potential problems of RHuEPO treatment.

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