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The synthesis of cyclopropano nucleosides
1Institute of Physical and Chemical Research (RIKEN), Saitama, Japan.
Nucleic Acids Symposium Series
|January 1, 1992
Abstract:
A tricyclic, fused cyclopropano nucleoside 8 containing a ketal group was synthesized by the one-pot seven sequential reactions of a trimesylated allofuranosyl adenine derivative 6 with Mg(OMe)2. When KOH was used instead of Mg(OMe)2, an alpha, beta-unsaturated ketonucleoside 7 was obtained.