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Does a correlation between transaminase activity and the size of the liver in psoriatic children exist?
Irena Lechowska-Mazur1, Aldona Pietrzak, Janusz Urban
1Department of Dermatology, Medical University of Lublin.
Abstract:
Psoriasis is a systemic disease. On the basis of the literature it has been stated that there is a possibility that a disease which is going on in the skin may be reflected by the increase in the activity of the hepatic cell. This activity was estimated by the McLaghan units, concentration of aspartate and alanine aminotransferases and morphometric measurements of the liver in 3 oblong dimensions. The study was conducted on 56 children suffering from psoriasis and 32 healthy ones matched with sex and age. None of the investigated parameters differs statistically between ill and healthy children. No association was stated between psoriasis and the enlargement of the liver dimensions by means of ultrasonography or the McLaghan units, ALAT and ASPAT.