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Differentiation therapy
Alexander I Spira1, Michael A Carducci
1Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, CRB Room 1M89, Baltimore, MD 21231, USA. spiraal@jhmi.edu
Current Opinion in Pharmacology
|August 7, 2003
Abstract:
Differentiation therapy is an area of oncology that is in its infancy. Theoretically, the concept of differentiation therapy involves turning a cancer cell "off" biologically and reverting to a more "benign" phenotype. Many agents have been studied over the past few years, with many already either in use clinically or showing future promise.