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[New thrombophilia markers in digestive tract neoplasia]
V Parisi1, F Capasso, L Pudore
1Unità Operativa Complessa di Chirurgia Oncologica C, Istituto Nazionale Tumori Fondazione Pascale, Napoli.
Tumori
|August 9, 2003
Abstract:
Haemostatic system compounds not routinely studied, have been evaluated to define the individual risk of VTE (venous thromboembolism) and to influence the prognosis using selective drugs. Significantly high values of fibrinogen, free-TFPI, F1 + 2 fragments and TAT complexes on coagulation side and PAI-1 and TAFI on fibrinolysis side have been detected. Thrombin seems to have a role in the inhibition of TAFI dependent fibrinolysis not inhibited by heparin.