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Jeremiah P Malerich1, Dirk Trauner

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Journal of the American Chemical Society
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In-vitro Mutagenesis01:16

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In vitro Mutagenesis01:16

In vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.