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Severe intoxication after an intentional overdose of amlodipine

L Rasmussen1, S E Husted, S P Johnsen

  • 1Department of Anaesthesiology Silkeborg County Hospital, Epidemiology and Social Medicine, University of Aarhus, Denmark.

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Toxidromes: Clinical Features

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Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
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Drug toxicity: Idiosyncratic Reactions01:16

Drug toxicity: Idiosyncratic Reactions

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Drug Toxicity: Dose-Dependent Reactions

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Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

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