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[Microbicidal effect of Lautercide, a new disinfectant]
J Kneiflová1, M Slosárek, V Melicherciková
1Státní zdravotní ústav, Praha.
Ceskoslovenska Epidemiologie, Mikrobiologie, Imunologie
|December 1, 1992
Summary
Lautercide, a new disinfectant, effectively kills bacteria and fungi at low concentrations. However, it is ineffective against bacterial spores and certain resistant viruses, limiting its broad-spectrum disinfection capabilities.
Area of Science:
- Microbiology
- Disinfectant Efficacy Studies
Context:
- Evaluation of novel disinfectants is crucial for infection control in healthcare, veterinary, and public hygiene settings.
- Standardized testing methods are essential for assessing the antimicrobial spectrum and efficacy of chemical agents.
Purpose:
- To determine the bactericidal, fungicidal, and virucidal activity of Lautercide, a disinfectant containing coconut acid acetate amine.
- To establish optimal concentrations and exposure times for Lautercide against various microbial and viral agents.
- To identify limitations of Lautercide, particularly against resistant microorganisms and viruses.
Summary:
- Lautercide demonstrated significant bactericidal and fungicidal effects against common pathogens like Staphylococcus aureus, Escherichia coli, and Candida albicans within 2-10 minutes at 0.04%-0.5% concentrations.
- The disinfectant was ineffective against Bacillus subtilis spores, even at a 10% concentration with a 32-minute exposure.
- Mycobacteria inactivation varied: Mycobacterium tuberculosis and M. fortuitum required 15 minutes, while M. avium needed a 10% concentration for 60 minutes.
- Lautercide showed no efficacy against small, non-enveloped viruses.
Impact:
- Recommends Lautercide for one-stage disinfection and cleaning in healthcare, veterinary, and communal hygiene at a 1% aqueous solution.
- Suggests a 5% Lautercide solution with 30-minute exposure for pre-cleaning contaminated materials.
- Specifies concentrations and exposure times for mycobacterial disinfection: 5% for 10 minutes (M. tuberculosis, M. fortuitum) and 10% for 60 minutes (M. avium).