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Ciprofloxacin-induced acute interstitial nephritis and autoimmune hemolytic anemia
1Division of Renal Medicine, Department of Internal Medicine, Tan Tock Seng Hospital, Singapore, Singapore. Salim_Lim@ttsh.com.sg
Renal Failure
|August 13, 2003
Abstract:
Ciprofloxacin has been associated with several side effects including interstitial nephritis and hemolytic anemia. The combination of both side effects is extremely rare. In this report, we describe a case of ciprofloxacin-induced interstitial nephritis and autoimmune hemolytic anemia. Hemolytic anemia improved after stopping the drug and initiation of steroid therapy. Unfortunately, acute interstitial nephritis was irreversible and the patient developed end-stage renal disease.