Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Metabolic acidosis.

Salim Lim1

  • 1Department of Internal Medicine, Husada Hospital, Jakarta.

Acta Medica Indonesiana
|October 17, 2007
PubMed
Summary
This summary is machine-generated.

Acute metabolic acidosis in critically ill patients has two main types: high anion gap and hyperchloremic. Treatment for organic acidosis, like lactic acidosis, focuses on improving oxygenation, as sodium bicarbonate showed no benefit.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Blockade of renin-angiotensin-aldosterone system in kidney and heart disease: how much do we need?

Acta medica Indonesiana·2008
Same author

Recent update in the management of hypertension.

Acta medica Indonesiana·2008
Same author

Approach to hyperkalemia.

Acta medica Indonesiana·2007
Same author

Secondary hyperparathyroidism and calcium phosphate control in a hemodialysis population.

Acta medica Indonesiana·2007
Same author

Approach to hypokalemia.

Acta medica Indonesiana·2007
Same author

Ciprofloxacin-induced acute interstitial nephritis and autoimmune hemolytic anemia.

Renal failure·2003
Same journal

Mastery Learning in Intestinal Ultrasound Training: A Meaningful Step Forward, With Miles Still to Go.

Acta medica Indonesiana·2026
Same journal

The Validity and Reliability of the Indonesian Version of Post-Intensive Care Syndrome Questionnaire (PICSQ) for Intensive Care Unit Survivors.

Acta medica Indonesiana·2026
Same journal

Effects of Garcinia mangostana Peel Extract on Glycemic Control in Type 2 Diabetes Mellitus: A Systematic Review of Human Studies.

Acta medica Indonesiana·2026
Same journal

Acromegaly in an Elderly Woman.

Acta medica Indonesiana·2026
Same journal

Current Situation and Global Perspective of Nipah Virus.

Acta medica Indonesiana·2026
Same journal

Cytomegalovirus Encephalitis and Cerebral Toxoplasmosis in an Immunocompetent Patient: A Rare Case Report.

Acta medica Indonesiana·2026
See all related articles

Area of Science:

  • Nephrology and Critical Care Medicine
  • Acid-Base Physiology and Pathophysiology

Background:

  • Acute metabolic acidosis is a common complication in critically ill patients.
  • It is classified into high anion gap (e.g., lactic acidosis, ketoacidosis) and hyperchloremic (e.g., bicarbonate loss, renal tubular acidosis) forms.
  • Causes vary, including endogenous acid accumulation, bicarbonate loss, renal failure, and toxic ingestions.

Purpose of the Study:

  • To review the causes and treatment controversies of acute metabolic acidosis in critically ill patients.
  • To highlight the challenges in managing organic acidosis, such as lactic acidosis.

Main Methods:

  • Review of existing literature on acute metabolic acidosis.
  • Analysis of treatment strategies, particularly for organic acidosis.

Related Experiment Videos

  • Discussion of the efficacy of sodium bicarbonate therapy.

    • Main Results:

    • Effective treatment for organic acidosis involves addressing the underlying cause, primarily by improving tissue oxygenation to cease acid production.
    • Sodium bicarbonate administration in acute organic acidosis did not reduce morbidity or mortality, despite improving acid-base parameters.

    Conclusions:

    • Optimal treatment strategies for acute metabolic acidosis require further investigation.
    • Focus on improving tissue oxygenation is crucial for managing organic acidosis.
    • The role and efficacy of sodium bicarbonate in acute metabolic acidosis remain controversial and potentially ineffective for improving outcomes.