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Androgen effects on body composition.

Shalender Bhasin1, Linda Woodhouse, Thomas W Storer

  • 1Division of Endocrinology, Metabolism and Molecular Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA. sbhasin@ucla.edu

Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society
|August 14, 2003
PubMed
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This review examines how androgens, like testosterone, influence body fat, muscle mass, and physical function. It analyzes testosterone

Area of Science:

  • Endocrinology
  • Sports Medicine
  • Human Physiology

Background:

  • Androgens play a critical role in physiological differences between hypogonadal and eugonadal men.
  • Understanding androgen effects on body composition and muscle is crucial for men's health.

Purpose of the Study:

  • To review existing research on testosterone's impact on body composition, fat metabolism, and muscle anabolism.
  • To present dose-response relationships of testosterone administration.

Main Methods:

  • Literature review of studies investigating testosterone's effects.
  • Analysis of data from studies involving various testosterone doses (physiologic and supraphysiologic).
  • Inclusion of studies with and without exercise interventions.

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Main Results:

  • Testosterone influences body fat, muscle size, and performance.
  • Dose-response relationships are evident in various populations.
  • Exercise modulates testosterone's effects on body composition.

Conclusions:

  • Testosterone administration impacts body composition and muscle anabolism.
  • The effects of testosterone vary based on dose, exercise, and individual health status.
  • Further research is needed to fully elucidate androgenic effects in diverse male populations.