Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Prostate brachytherapy: current states and future prospects].

P Nickers1, J M Deneufbourg

  • 1Département de radiothérapie-oncologie, CHU de Liège, domaine universitaire du Sart-Tilman B 35, 4000, Liège, Belgique. Philippe.Nickers@skynet.be

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique
|August 14, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Not Available].

Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg·2018
Same author

[Inflammatory and immune biomarkers of radiation response].

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2018
Same author

[Cancer, radiotherapy and immune system].

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2017
Same author

[Intraprostatic fiducials in stereotactic radiotherapy for prostate cancer].

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2016
Same author

[Permanent iodine-125 implants brachytherapy: results after 10 years of experience in Liège University Hospital].

Revue medicale de Liege·2014
Same author

A new laparoscopic method of bowel radio-protection before pelvic chemoradiation of locally advanced cervix cancers.

Surgical endoscopy·2014
Same journal

White paper on radiotherapy in France: Ten objectives to strengthen one of the major modalities of cancer treatment.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2026
Same journal

Contemporary survival outcomes of patients with isolated nodal recurrences of breast cancer: A population-based study.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2026
Same journal

Factors affecting the stability of deep inspiration breath-holding in radiotherapy for left-sided breast cancers.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2026
Same journal

Incidence and outcomes of radiation-induced sarcomas following radiotherapy for low-grade non-Hodgkin lymphomas: A population-based study.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2026
Same journal

Radiotherapy as a curative strategy for primary pleural indolent lymphomas: Analytical guidelines based on literature and an illustrative population-based case series.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2026
Same journal

Cone-beam computed tomography-based radiomics for tumour regression assessment during radiotherapy of non-small-cell lung cancer.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2026
See all related articles

Brachytherapy offers prostate cancer patients excellent cure rates comparable to surgery, while preserving function. This radiation technique is also effective for boosting treatment in intermediate-risk cases.

Area of Science:

  • Radiation Oncology
  • Urologic Oncology

Background:

  • Prostate radiotherapy involves various techniques, each with unique benefits and limitations.
  • Brachytherapy, a form of internal radiation, is increasingly recognized for its role in prostate cancer management.

Purpose of the Study:

  • To delineate the characteristics, applications, and limitations of brachytherapy in prostate cancer radiotherapy.
  • To compare brachytherapy with surgery and external beam radiotherapy for prostate cancer treatment.

Main Methods:

  • Review of brachytherapy characteristics, including I(125) and Pd(103) permanent implants.
  • Analysis of brachytherapy's efficacy as a boosting method for intermediate or unfavorable prognosis tumors.
  • Evaluation of treatment outcomes, including cure rates, organ motion control, patient positioning, and toxicity.

Related Experiment Videos

Main Results:

  • Permanent implants (I(125), Pd(103)) offer comparable cure rates to surgery and external beam radiotherapy for good prognosis tumors, while sparing rectal and erectile function.
  • Brachytherapy excels as a boosting method for intermediate/unfavorable prognosis tumors, allowing high doses per fraction (10 Gy) with alpha/beta of 1.5 Gy.
  • Phase II trials report encouraging biological control rates of 80-90%.
  • Irradiation heterogeneity within the target volume may enhance cure probability but can lead to urethral overdosage and increased toxicity in specific patient groups.

Conclusions:

  • Brachytherapy is a valuable option for prostate cancer, offering competitive cure rates and functional preservation.
  • Its role as a boosting technique for higher-risk cancers shows promising results.
  • Optimizing the integration of brachytherapy with other modalities can improve treatment outcomes for prostate cancer.