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Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
[Formation of complexes of ascorbic acid and biological ligands]
V V Vereshchaka1, O M Kharlamova
1Bogomolets Institute of Physiology, NAS of Ukraine, Kyiv.
Abstract:
Ascorbic acid has wide usage in medical practice for treatment some diseases caused by degeneration of connective tissue. Ascorbic acid has strong reduce properties. This article is dedicated to investigating complexation properties of ascorbic acid with components of biomembrans-bioligands: the most widespread aminoacids of connective tissue, phosphatidylholine, ATP, calcium salts, proteins. The investigations realised give the opportunity to make the conclusion that ascorbic acid has some complexation properties with different bioligands. But the stability of these complex products is different. And these stability variationes are described in this article.
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