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Updated: May 22, 2026

Intradermal Microdialysis: An Approach to Investigating Novel Mechanisms of Microvascular Dysfunction in Humans
Published on: July 21, 2023
[Features of systemic microcirculation in patients with chronic dermatoses]
Abstract:
We investigated the parameters of microcirculation of eyes in women of 36-55 years age with atopic dermatitis, microbic eczema and diffuse alopecia. In persons with atopic dermatitis the signs of non-uniformity of capillary caliber and their branching were observed. These abnormalities were accompanied by an increase in the quantities of functioning anastomoses, loops and corners of capillaries. Abnormalities of microcirculation which accompany microbic eczema included alterations in microvessel parallelism, microaneurysm, venous sacculation, pathological forms of branching, vascular new growth, an increased number of functioning anastomose and presence of avascular fields. Diffuse alopecia was characterized by the venous sacculation, branching microveins, non-uniformity of their diameter and spasm of arteriols.
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