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MR imaging of ankylosing spondylitis
Emily N Vinson1, Nancy M Major
1Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.
Seminars in Musculoskeletal Radiology
|August 16, 2003
Summary
Ankylosing spondylitis (AS) is an inflammatory disease associated with HLA-B27, primarily affecting the sacroiliac joints and spine. This study details its magnetic resonance imaging features in the axial skeleton.
Area of Science:
- Rheumatology
- Radiology
- Immunogenetics
Background:
- Ankylosing spondylitis (AS) is a seronegative spondyloarthropathy linked to HLA-B27.
- It characteristically involves inflammation of entheses and joints, leading to radiographic ankylosis.
- Key sites include sacroiliac joints and the spine, with other joints less commonly affected.
Purpose of the Study:
- To describe the magnetic resonance imaging (MRI) features of ankylosing spondylitis.
- To correlate MRI findings with the pathophysiology and clinical presentation of AS.
- To highlight considerations for radiographic evaluation in AS patients with trauma.
Main Methods:
- Review of basic pathophysiology and clinical findings in AS.
- Detailed description of typical MRI features of AS in the axial skeleton.
- Discussion of special considerations for radiographic trauma evaluation in AS.
Main Results:
- AS exhibits specific MRI characteristics within the axial skeleton, particularly involving the sacroiliac joints and spine.
- Understanding these features aids in diagnosing AS and differentiating it from other conditions.
- Radiographic evaluation in trauma settings requires awareness of AS-related changes.
Conclusions:
- MRI is crucial for visualizing the axial skeletal manifestations of ankylosing spondylitis.
- Accurate interpretation of imaging findings is essential for patient management.
- Special attention is needed when evaluating AS patients presenting with trauma.