[Origin and development of the theory of angiogenesis]

About some 400 years ago, people observed the formation of vascular genesis around the tumors. In 1971, Folkman, a professor with Harvard University, put forward that the growth and metastasis of tumor were determined by the formation of blood vessels. Prevention of angiogenesis can inhibit the growth of tumors. Since then, the studies on angiogenesis rapidly developed and was involved in many other clinical fields other than oncology. Inhibition of angiogenesis and therapeutic angiogenesis has become two very promising projects of treatment.