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Memory functions in persons with dental amalgam.

K Dalen1, G B Lygre, H Kløve

  • 1Department of Clinical Neuropsychology, University of Bergen, Jonas Liesvei 91, N-5009, Bergen, Norway. k.dalen@psych.uib.no

Journal of Dentistry
|August 21, 2003
PubMed
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Individuals reporting reactions to dental amalgam showed no differences in memory or psychophysiological function compared to controls. This study found no correlation between amalgam exposure and cognitive performance or attention.

Area of Science:

  • Neuroscience
  • Psychology
  • Toxicology

Background:

  • Self-reported reactions to dental amalgam are common.
  • Concerns exist regarding potential neurological effects of amalgam exposure.
  • Previous research has yielded mixed results on amalgam's impact on cognitive function.

Purpose of the Study:

  • To compare memory and psychophysiological variables between individuals with and without self-reported dental amalgam reactions.
  • To investigate potential dose-response relationships between amalgam exposure and cognitive function.

Main Methods:

  • Comparison of memory performance using the Wechsler Memory Scale-Revised.
  • Assessment of psychophysiological measures, including skin conductance.
  • Matching of participants based on age, education, and amalgam load.

Related Experiment Videos

  • Analysis of dose-response relationships between amalgam exposure and memory variables.

    • Main Results:

    • Amalgam patients and controls exhibited similar performance on memory variables, attention, concentration, and delayed recall.
    • No significant differences in skin conductance were observed between the two groups.
    • No correlation was detected between memory variables and the amount of amalgam exposure.

    Conclusions:

    • Self-reported reactions to dental amalgam do not appear to be associated with measurable deficits in memory or attention.
    • Psychophysiological measures do not differentiate between individuals with and without amalgam-related symptoms.
    • Current evidence suggests no link between amalgam exposure levels and cognitive function in this cohort.