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Outbreak of Mycobacterium abscessus infection after soft tissue augmentation
Brian R Toy1, Paul Jarrod Frank
1Department of Dermatology, New York University Medical Center, 560 1st Avenue, H-100, New York, NY 10016, USA. dr_toy@yahoo.com
Background:
Illicit soft-tissue augmentation performed in New York City resulted in an outbreak of Mycobacterium abscessus infection in 2002.
Objective:
To report two cases of women who developed tender, subcutaneous nodules of the face and buttocks after illicit soft-tissue augmentation with a hyaluronic acid derivative.
Methods:
Two case reports are presented, and the literature is reviewed.
Results:
Empiric treatment with clarithromycin (for M. abscessus infection) and prednisone (for foreign body reaction) resulted in clearance of lesions.
Conclusion:
Contaminated or impure material used for soft-tissue augmentation can result in a clustered outbreak of infection or foreign body reaction.