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Published on: September 12, 2019
Extraorbital sebaceous carcinoma with rapidly developing visceral metastases
Deniz Güney Duman1, Berrin Bagci Ceyhan, Turgay Celikel
1Department of Internal Medicine, Marmara University Hospital, 81060 Ciftehavuzlar, Istanbul, Turkey. drduman@excite.com
Summary
Extraorbital sebaceous carcinoma (SC) can aggressively metastasize despite negative margins. This rare skin cancer may have a poor prognosis, requiring caution from dermatologic surgeons.
Area of Science:
- Dermatologic oncology
- Cutaneous oncology
Background:
- Extraorbital sebaceous carcinoma (SC) is a rare skin cancer.
- Typically, SC has a good prognosis regarding metastasis and survival.
Observation:
- This case presents an unusual, aggressive form of extraorbital SC.
- The tumor metastasized rapidly despite local excision with negative margins.
Findings:
- Rapid and fatal internal organ metastases occurred post-excision.
- Docetaxel chemotherapy was ineffective after distant metastases developed.
Implications:
- Extraorbital SC can exhibit a poor prognosis and aggressive behavior.
- Dermatologic surgeons must be vigilant for local recurrence and distant metastasis risks.
