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Updated: Jul 26, 2026

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
The effect of urethral instrumentation on uroflowmetry
1Department of Urology, Emory University School of Medicine, and Atlanta Veterans Affairs Medical Center, Atlanta, Georgia 30322, USA. muta.issa@med.va.gov
Flexible cystoscopy significantly impacts peak urinary flow rate (Qmax) measurements. Uroflowmetry data collected after urethral instrumentation should be excluded to avoid falsely indicating treatment improvement.
Area of Science:
- Urology
- Medical Instrumentation
Background:
- Uroflowmetry is a key diagnostic tool for lower urinary tract symptoms.
- Flexible cystoscopy is commonly used for urethral and bladder evaluation.
- Accurate uroflowmetry is crucial for assessing treatment efficacy in conditions like benign prostatic obstruction.
Purpose of the Study:
- To prospectively assess the effect of flexible cystoscopy on uroflowmetry, specifically peak urinary flow rate (Qmax).
- To determine if urethral instrumentation influences subsequent Qmax measurements.
Main Methods:
- 32 patients undergoing flexible cystoscopy had uroflowmetry performed immediately before and after the procedure.
- Exclusion criteria included active urethral stricture or urinary infection.
- Post-void residual volume (PVR) was measured, and bladder volume was normalized with saline before post-procedure uroflowmetry.
Main Results:
- Mean Qmax decreased significantly after flexible cystoscopy (16.9 mL/s pre vs. 13.3 mL/s post, P=0.029).
- A mean percentage difference of +27% indicated higher Qmax before instrumentation.
- A notable proportion of patients (up to 25%) showed a reduction in Qmax post-procedure.
Conclusions:
- Urethral instrumentation via flexible cystoscopy significantly alters Qmax.
- Using post-instrumentation uroflowmetry can lead to a misleading "improvement" in Qmax by up to 27%.
- Excluding post-instrumentation uroflowmetry data is essential for accurate assessment of therapies for conditions like benign prostatic obstruction.
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