Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Wheel access duration in rats: II. Day-night and within-session changes.

Roelof Eikelboom1, Sara B Lattanzio

  • 1Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada. reikelbo@wlu.ca

Behavioral Neuroscience
|August 23, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acquisition and persistence of intermittent access-induced escalated sucrose intake in male rats.

Physiology & behavior·2022
Same author

Digital dementia in the internet generation: excessive screen time during brain development will increase the risk of Alzheimer's disease and related dementias in adulthood.

Journal of integrative neuroscience·2022
Same author

Sucrose solution concentration and the intermittent access induced consumption increase.

Physiology & behavior·2021
Same author

Reduced caloric intake allows access-induced consumption differences to emerge with concentrated sucrose solutions.

Physiology & behavior·2021
Same author

Intermittent access to a sucrose solution for rats causes long-term increases in consumption.

Physiology & behavior·2016
Same author

Can overeating induce conditioned taste avoidance in previously food restricted rats?

Physiology & behavior·2009
Same journal

Hippocampal communication with the anterior olfactory nucleus is necessary for context-dependent odor memory.

Behavioral neuroscience·2026
Same journal

Biological sex and normative cognitive aging across spatial learning, flexibility, and working memory in Fischer 344 rats.

Behavioral neuroscience·2026
Same journal

Defensive antinociception and antipredatory responses in prey threatened by distinct odoriferous cues from Felis silvestris catus.

Behavioral neuroscience·2026
Same journal

Taste exposure during different developmental phases impacts aversion learning in adult rats.

Behavioral neuroscience·2026
Same journal

Structural neuroanatomy of semantic retrograde memory in older adults.

Behavioral neuroscience·2026
Same journal

Oxytocin prevents cocaine-induced high-affect 50-kHz vocalizations in female rats.

Behavioral neuroscience·2026
See all related articles

Wheel running in rats increased significantly when access occurred during the dark phase, but not the light phase. Longer access durations amplified running behavior, suggesting a potential addiction model.

Area of Science:

  • Behavioral Neuroscience
  • Animal Models of Addiction
  • Chronobiology

Background:

  • Rodent models are crucial for understanding complex behaviors.
  • Wheel running is a common measure of spontaneous physical activity in rodents.
  • Previous research has explored factors influencing rodent activity patterns.

Purpose of the Study:

  • To investigate the impact of time of day and duration of wheel access on running behavior in rats.
  • To explore the potential of wheel running as a model for addiction.

Main Methods:

  • Young male rats were provided with controlled durations (2 hours) of wheel access during either the light or dark phase.
  • Running activity was monitored over 24 days.
  • Different durations of dark phase access (1 hour vs. 4 hours) were also tested.

Related Experiment Videos

Main Results:

  • Running behavior increased fourfold in rats with dark phase access over 24 days.
  • Rats with light phase access showed consistently low running levels.
  • Longer (4-hour) dark phase access resulted in significantly greater running increases compared to shorter (1-hour) access.

Conclusions:

  • Time of day critically influences the development of wheel running behavior in rats.
  • Increased duration of access potentiates running behavior, mirroring aspects of addiction.
  • Wheel running exhibits similarities to cocaine self-administration, supporting its use as an addiction model.