Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Spatial modelling of individual-level parasite counts using the negative binomial distribution.

N Alexander1, R Moyeed, J Stander

  • 1Infectious Disease Epidemiology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. neal.alexander@lshtm.ac.uk

Biostatistics (Oxford, England)
|August 23, 2003
PubMed
Summary

We developed a spatial model for parasite count data, revealing how Wuchereria bancrofti spread relates to distance. This model aids in understanding lymphatic filariasis epidemiology and control strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High repetition-rate foam targetry for laser-plasma interaction experiments: Concept and preliminary results.

The Review of scientific instruments·2024
Same author

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

Physical review letters·2024
Same author

The availability of short-handled videolaryngoscopes in obstetric anaesthesia.

International journal of obstetric anesthesia·2023
Same author

Challenges and opportunities of sharing animal health data for research and disease management: a case study of bovine tuberculosis.

Revue scientifique et technique (International Office of Epizootics)·2023
Same author

Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment.

Physical review letters·2022
Same author

Ion acceleration from microstructured targets irradiated by high-intensity picosecond laser pulses.

Physical review. E·2020

Area of Science:

  • Spatial statistics
  • Parasitology
  • Epidemiology

Background:

  • Lymphatic filariasis, caused by Wuchereria bancrofti, is a significant human parasitic disease.
  • Understanding the spatial distribution of parasite counts is crucial for effective control.

Purpose of the Study:

  • To present a novel spatial model for analyzing highly dispersed count data.
  • To apply this model to individual-level Wuchereria bancrofti counts.
  • To interpret the findings for lymphatic filariasis epidemiology and control.

Main Methods:

  • Utilized a negative binomial distribution model to handle over-dispersed count data.
  • Quantified spatial association using a characteristic length parameter.
  • Incorporated individual-level covariates like age and sex through demographic surveillance and mapping.

Related Experiment Videos

Main Results:

  • The spatial model effectively captures the mean and correlation of Wuchereria bancrofti counts.
  • A characteristic length was derived, indicating the distance over which spatial correlation halves.
  • Individual covariates were integrated, providing a more nuanced understanding of parasite distribution.

Conclusions:

  • The developed spatial model offers a robust framework for analyzing parasitic disease data.
  • Results provide insights into lymphatic filariasis spatial epidemiology.
  • The model's findings have potential implications for optimizing control programs.