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Updated: Aug 23, 2026

Coherent anti-Stokes Raman Scattering (CARS) Microscopy Visualizes Pharmaceutical Tablets During Dissolution
Published on: July 4, 2014
[A study on the decomposition kinetics of vitamin C tablet]
Abstract:
Under the condition of relative humidity less than the critical relative humidity, the discoloration rate and decomposition rate of vitamin C tablet and the discoloration rate of vitamin C tablet in solution were studied at temperatures 60-90 degrees C and relative humidities 60%-80%. The general equation of the relationship between the apparent rate constant k, absolute temperature T and relative humidity RH is: k = k' exp(-E/RT) exp(mRH), where k' and m are constants, E is apparent activation energy. The values of k', m and E for discoloration, decomposition and discoloration in solution are different.
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