Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Right bundle branch block and coved-type ST-segment elevation mimicked by acute cholecystitis.

Masato Furuhashi¹, Kikuya Uno, Shin-Ichiro Satoh

¹Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan. furuhasi@sapmed.ac.jp

Circulation Journal : Official Journal of the Japanese Circulation Society

|August 27, 2003

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Efficacy and safety of a needle-type knife that injects fluid through its tip compared with a conventional needle-injection knife for colorectal endoscopic submucosal dissection: a randomized controlled trial (with video).

Surgical endoscopy·2025

Same author

Efficacy and safety of endoscopic submucosal dissection versus endoscopic papillectomy for managing laterally spreading duodenal papillary tumors.

Clinical endoscopy·2025

Same author

Efficacy of Texture and Color Enhancement Imaging for Identification of Colorectal Polyps: A Prospective Crossover Randomized Trial.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society·2025

Same author

Patients with symptomatic uncomplicated diverticular disease have high fecal bile acid concentrations.

Frontiers in medicine·2025

Same author

Improving Operator Depth Vision in Gastrointestinal Endoscopy: A Pilot Study of a New Three-dimensional Imaging System.

DEN open·2025

Same author

Pemafibrate for treating MASLD complicated by hypertriglyceridaemia: a multicentre, open-label, randomised controlled trial study protocol.

BMJ open·2024

Acute cholecystitis can mimic Brugada syndrome, causing ST-segment elevation on ECGs. This Brugada-type ST shift resolved with inflammation and was reproducible with sodium channel blockers.

Area of Science:

Cardiology
Gastroenterology
Electrophysiology

Background:

Brugada syndrome is a genetic disorder characterized by abnormal ECG findings and increased risk of sudden cardiac death.
Acute cholecystitis is gallbladder inflammation, typically presenting with abdominal pain and fever.

Observation:

A 69-year-old woman presented with acute cholecystitis that mimicked a Brugada-type ST shift on her electrocardiogram (ECG).
The patient had no prior cardiac history, syncope, or family history of sudden death.
The ECG abnormalities resolved as the cholecystitis subsided.

Findings:

This case demonstrates a Brugada-type ST shift associated with acute cholecystitis.
Intravenous pilsicainide, a sodium channel blocker, successfully reproduced the Brugada-type ST shift.

Related Experiment Videos

This is the first reported instance of this ECG phenomenon in conjunction with acute cholecystitis.

Implications:

Acute cholecystitis should be considered in the differential diagnosis of Brugada-type ST shifts, especially in patients without typical risk factors.
This association highlights the potential for non-cardiac conditions to unmask or mimic cardiac electrical abnormalities.
Further research may elucidate the underlying mechanisms connecting gallbladder inflammation and cardiac electrophysiology.