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Related Experiment Videos

Steady-state sequence synthesis and its application to efficient fat-suppressed imaging.

William R Overall1, Dwight G Nishimura, Bob S Hu

  • 1Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA. wro@stanford.edu

Magnetic Resonance in Medicine
|August 27, 2003
PubMed
Summary

A new algorithm designs steady-state pulse sequences for artifact-free MRI. This technique enables effective fat suppression in imaging, maintaining standard scan times for improved diagnostic clarity.

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Area of Science:

  • Magnetic Resonance Imaging
  • Pulse Sequence Design
  • Signal Processing

Background:

  • Conventional steady-state free precession (SSFP) sequences often suffer from banding artifacts due to off-resonant spins.
  • Achieving effective and robust fat suppression in SSFP imaging remains a challenge.
  • The Shinnar-Le Roux (SLR) transform provides a framework for designing complex RF pulses.

Purpose of the Study:

  • To develop a novel synthesis algorithm for generating refocused SSFP sequences with arbitrary magnetization profiles.
  • To apply this algorithm for creating SSFP sequences with flat profiles to eliminate banding artifacts.
  • To utilize the algorithm for developing SSFP sequences capable of broad steady-state fat suppression.

Main Methods:

  • A new synthesis algorithm based on the Shinnar-Le Roux (SLR) transform was developed.

Related Experiment Videos

  • The algorithm allows for periodic oscillation of RF excitation magnitude and phase to control magnetization profiles.
  • Refocused-SSFP sequences with flat and attenuated signal profiles were designed and implemented.

    • Main Results:

    • The developed algorithm successfully generated refocused-SSFP sequences with flat profiles, mitigating banding artifacts.
    • Sequences designed for steady-state fat suppression demonstrated a broad region of signal attenuation.
    • Preliminary results showed excellent agreement between theoretical predictions and experimental signal levels.
    • 3D fat-suppressed images of the human leg were acquired in 44 seconds, showcasing clinical applicability.

    Conclusions:

    • The novel SLR-based algorithm enables the creation of artifact-free, refocused SSFP sequences with tailored magnetization profiles.
    • This technique offers a robust solution for steady-state fat suppression in MRI.
    • The developed sequences are clinically applicable, allowing for fast, fat-suppressed 3D imaging.