Methods, architecture, evaluation and usability of a case-based antibiotics advisor
Related Experiment Video
Updated: Sep 20, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Lothar Gierl1, Dagmar Steffen, Dusan Ihracky
1Institute for Medical Informatics and Biometry, University of Rostock, Rembrandtstrasse 16/17, D-18055 Rostock, Germany. lothar.gierl@medzin.uni-rostock.de
Abstract:
In this paper, we discuss the usability of an antibiotics therapy adviser, with a broad, complex spectrum of functions which we have developed within the ICONS project. We present the architecture of the system, case-based reasoning methods used, steps and results of medical evaluations, which are concerning the quality of the recommended therapies, the user friendliness of the system and the interpretation of laboratory results. Furthermore, we discuss problems of transferability of such a system from one site to another as well as problems of local susceptibility patterns and individual dose regimens.
More Related Videos
09:59Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
Published on: July 21, 2023
12:58A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
Published on: May 25, 2017
Related Concept Videos
Automated Microbial Diagnostics
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Methods of Documentation VI: Case Management Model
For example, a patient with a chronic illness...
Antimicrobial Effectiveness
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Clinical Significance of Antibiotic Resistance