Related Experiment Video
Updated: Jul 29, 2026

Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices
Published on: January 14, 2014
[State of human bronchopulmonary apparatus under hypobaric hypoxia and its adaptation to that condition]
A N Bulakhov1, A G Nikolaeva, E A Dotsenko
1Republic Lipid Diagnostic Center, Vitebsk, Byelorussia.
Abstract:
The influence of hypobaric hypoxia (HH) on the bronchial tree smooth muscle state at 208 men was investigated. It was shown, that HH relaxes smooth muscle of bronchus, eliminating the phenomena of bronchismus, is activities mucocilsary clearance. The increase of the forced speed of an exhalation for 1 sec in one month after ending a course (2.5 + 0.25 l/sec against 2.1 + 0.13 l/sec) was marked. In 6 months after ending a course of HH the forced speed of an exhalation for the first second continues to grow and is statistically authentically above initial (2.6 + 0.15 l/sec). The increase of an Teffno index was marked which in 6 months of treatment comes nearer to 100% (97.5 + 6.1 against 79 + 2.6%).
Related Concept Videos
Physiological Control of Respiration
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Alterations in Respiration II
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes include...
Hypoxia
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
Hyperpnea and Hyperventilation
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Atelectasis II: Pathophysiology

