Related Experiment Videos
[Biologic function of p21WAF1/CIP1 gene and its association with carcinogenesis]
Yaguang Xi1, Yinghui Ren, Xiulan Su
1Peking University School of Oncology, Department of Genetic, Beijing Institute for Cancer Research, Beijing 100034, China.
Abstract:
p21WAF1/CIP1 gene is known for a most important cell cycle regulator as well as its roles in appoptosis and differentiation. This review focuses on p21WAF1/CIP1 gene functions and its association with carcinogenesis. Better understanding of the structure and function of p21WAF1/CIP1 gene may help to comprehend molecular mechanisms of cancers and to facilitate diagnosis and treatment of malignancy.