Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Polymeric growth factor delivery strategies for tissue engineering.

Ruth R Chen1, David J Mooney

  • 1Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

Pharmaceutical Research
|September 2, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The CARM1 epigenetic enzyme inhibits cross-presenting dendritic cell function in cancer immunity.

Science (New York, N.Y.)·2026
Same author

Driving emerging technology to clinical impact.

Journal of the American Dental Association (1939)·2026
Same author

Implantable living materials autonomously deliver therapeutics using contained engineered bacteria.

Science (New York, N.Y.)·2026
Same author

Feeder-free generation of functional dendritic cells from human pluripotent stem cells.

Journal for immunotherapy of cancer·2026
Same author

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Hemostatic Tough Adhesives seal tissue and control hemorrhage.

Nature communications·2026

Polymeric delivery systems effectively deliver growth factors for tissue engineering, promoting regeneration in various tissues. Precise control over dose, location, and duration is key for successful tissue regeneration.

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Polymer Chemistry

Background:

  • Tissue engineering aims to restore or replace damaged tissues and organs.
  • Growth factors are crucial signaling molecules that direct cell behavior in tissue regeneration.

Purpose of the Study:

  • To review the application of polymeric delivery systems for growth factor delivery in tissue engineering.
  • To highlight the role of controlled release in enhancing tissue regeneration outcomes.

Main Methods:

  • Development of polymeric systems for delivering growth factor proteins.
  • Engineering systems for delivering genes encoding growth factors.
  • Utilizing cells engineered to secrete specific growth factors.

Main Results:

Related Experiment Videos

  • Successful application of growth factor delivery systems in animal models.
  • Positive outcomes in clinical trials demonstrating tissue regeneration.
  • Evidence supporting the regeneration of diverse tissue types using these methods.

Conclusions:

  • Polymeric delivery strategies offer precise control over growth factor administration.
  • Optimizing dose, location, and duration of growth factor delivery is critical for effective tissue regeneration.
  • Advanced polymeric systems are essential for the future of tissue engineering.