[Kidney transplantation in hyperimmunized patients ignoring the cross-match performed with historic sera]

To ignore the positivity of renal pretransplantation cross-match performed with peak sera remains a controversial practice. The present study concerns 11 renal transplantations after positive cross-match with peak sera and negative cross-match with current sera. The clinical results of these transplantations lead to the assumption that peak sera contained HLA antibodies not specific to the graft and non HLA antibodies responsible for the positivity of the cross-match.