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Potentiated antibodies to mu-opiate receptors: effect on integrative activity of the brain

V V Geiko1, T M Vorob'eva, O G Berchenko

  • 1Institute of Neurology, Psychiatrics, and Narcology, Ukrainian Academy of Medical Sciences, Kharkov.

Bulletin of Experimental Biology and Medicine
|September 2, 2003
PubMed

The effect of homeopathically potentiated antibodies to mu-receptors (10(-100) wt %) on integrative activity of rat brain was studied using the models of self-stimulation of the lateral hypothalamus and convulsions produced by electric current. Electric current was delivered through electrodes implanted into the ventromedial hypothalamus. Single treatment with potentiated antibodies to mu-receptors increased the rate of self-stimulation and decreased the threshold of convulsive seizures. Administration of these antibodies for 7 days led to further activation of the positive reinforcement system and decrease in seizure thresholds. Distilled water did not change the rate of self-stimulation and seizure threshold.

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